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I'm allergic to penicillin, so this is pretty much my best option. I'm terrified of the long list of sides effects on most medicines, but I've had this 3 times before for various conditions and it hasn't killed me. It works really well but it's so important that you keep taking it for the full duration. It usually starts working in 2- 3 days. As for side effects, I always get the metallic taste (I don't know why they list this as an uncommon side effect instead of common) as well as stomach pains and nausea. Never had diarrhea from it. My advice would be to take food with it or 30 mins before, and sit/stand for the next few hours. When you lie down, the symptoms are much worse, especially the nausea, cramps & metallic taste.

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Clarithromycin increases the plasma concentration of loratadine by inhibiting its hepatic metabolism thus increases its plasma level upto 40%.

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NTM may cause both asymptomatic infection and symptomatic disease in humans.

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The disk diffusion and dilution techniques for susceptibility testing against gram-positive and gram-negative bacteria should not be used for determining clarithromycin MIC values against mycobacteria.

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Usually avoid combinations; use it only under special circumstances.

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